Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
13. “Girlhood” (Céline Sciamma)
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
The economy will grow 3% for the first time in 10 years
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
No. Football punditry is a mug’s game. Better to have the benefit of hindsight. There have been 20 previous World Cups. Of those, Brazil (five titles) and Germany (four), are regular contenders. Home advantage helps, with host nations winning the trophy six times. But next year’s festival of football is being held in Russia, which has the lowest-ranked team in the tournament.
Trends and targets in antiviral phototherapy
New construction will provide luxury options for renters with deep pockets, mostly in the boroughs outside Manhattan. In Brooklyn, 6,527 new rental units are expected to hit the rental market next year, nearly twice the 3,802 units anticipated for Manhattan, according to Citi Habitats.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
In one tweet that was posted on Jan 10, Obama wrote, "Thank you for everything. My last ask is the same as my first. I'm asking you to believe - not in my ability to create change, but in yours."
Novel biosensing methodologies for ultrasensitive detection of viruses
斯德哥尔摩经济学院(Stockholm School of Economics)是今年排行榜上的大赢家，该学校的排名攀升16个位次，排在第28位，不仅排名晋升速度为年度最快，而且扭转了去年排名下滑11位的局面。
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Bolder lawyers will start working with more “sci-fi” programs that claim to predict the outcomes of legal disputes before they have reached court, by analysing similar cases and past rulings, opposition tactics and win/lose statistics, the success rates of certain lawyers before certain judges, and so on.
Her predecessor David Cameron placed fifth in CNNMoney's previous ranking in March 2015 with his salary of ￡142,500, then worth $214,800. May is only seventh.
Diagnostic technologies for COVID-19: a review
The CSI 300, which consists of 300 of the top A-shares traded on the Shanghai and Shenzhen exchanges, is down 7 per cent and will be shut for the remainder of the day.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Developer: Supermassive Games, Sony Computer Entertainment
As consumers in developing countries continue to shift to meat-based diets, grains and oilseeds used as livestock feed are expected to see support.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
6. Charlize Theron - $16.5 million
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Type A and Type B personality theory describes Type A individuals as outgoing, ambitious, rigidly organized, highly status-conscious, sensitive, impatient, anxious, proactive, and concerned with time management.
Antiviral drug discovery: broad-spectrum drugs from nature
China's best performances by subject this year come from Tsinghua University, with three top-10 places, and Peking University, with two top-10 places. Tsinghua University finishes eighth in both Architecture/Built Environment and in Engineering (Civil and Structural). Tsinghua comes in 10th place in the world's Materials Science subject rankings.
节目31 京剧《迎来春色换人间》，于魁智 托马斯（孔子学院学员）
Management and leadership skills are just one aspect of EMBAs. “It actually made an entrepreneur of me,” says one graduate. Nearly a third (31 per cent)of graduates have set up their own company, or are about to, since enrolling on their EMBA four or five years ago. FT data show that 91 per cent of the businesses are operating today.
Influenza neuraminidase: A druggable target for natural products
The three-day China Development Forum 2016 kicked off in Beijing.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Last week, Clinton campaign chairman John Podesta said that the former first lady's shortlist of potential running mates will include women, quickly leading to speculation that Clinton will consider Massachusetts Sen. Elizabeth Warren, a popular progressive, for an all-female ticket.
The role of biosensors in the detection of emerging infectious diseases
“These students have absolutely no free speech rights that were violated in this context."
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
12. Zoho CRM
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Comic skit “Big City Small Life”(Wang Ning, Chang Yuan and Ailun)
Recipient: Canadian Prime Minister Justin Trudeau
Shares in Hyundai and AmorePacific slid on Friday, down 4.4 per cent and 12.5 per cent respectively in late afternoon trading in Seoul.
We will improve mechanisms that give incentives and allow for and address mistakes so as to support those who are dedicated to their work and stand behind those who live up to their responsibilities. Every one of us in government must take an active approach to our work and have the courage to tackle the toughest problems, we must work closely with the people, using concrete action to make progress in development, and using genuine hard work to realize a bright future.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Fantastic Beasts and Where to Find Them will be released worldwide on November 18, 2016.
“纽约人正逐渐意识到，这一漫长的繁荣期已对我们眼中的经典纽约市容造成了破坏，”历史街区保护委员会(Historic Districts Council)的执行董事西蒙·班考夫(Simon Bankoff)说，他同时指出，2015年将是纽约市通过《地标建筑保护法》的50周年。“环顾左右，那些总被我们认为是一成不变的东西，却都在纷纷关门闭户。”
Inhibition of SARS coronavirus helicase by bismuth complexes
That is changing. One big 2013 move for benchmark Brent crude came in August, when international intervention in Syria seemed increasingly likely. But while the price of Brent, which is traded on London's IntercontinentalExchange, did rise by 5% on the threat of U.S.-led airstrikes, it didn't come close to the 2013 high.
Some hits have gone so far over the top they should be winded, yet instead keep on puffing gusts of hot air, including “Downton Abbey,” “Scandal” and “Revenge.” A new addition on ABC, “How to Get Away With Murder” was a fun substitute, a lurid nighttime soap opera about lawbreaking defense lawyers — “Law & Disorder.”
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Adapted from an online novel Queen of No.11 Agent, the TV series is about the adventure of a female slave Chu Qiao and her romance with a prince Yan Xun.
节目40 歌曲《难忘今宵》李谷一 张英席 白丽莎（孔子学院学员）、茹丝（孔子学院学员）、李天翼（孔子学院学员）、吴孟天（在华留学生）
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The estimates include earnings from movies, TV and endorsements from cosmetic and other companies. Bollywood star Deepika Padukone is the only newcomer on the list.
No.35 娜塔丽·波特曼娜塔丽·波特曼（Natalie Portman ，1981年6月9日－），出生在以色列，美国好莱坞著名女演员之一。她曾获得过金球奖，并获得奥斯卡奖提名。美国哈佛
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
WOLF HALL (PBS, April 5) In the season’s most promising piece of casting, Damian Lewis (“Homeland”) will play Henry VIII and the two-time Tony Award winner Mark Rylance will play Thomas Cromwell in this “Masterpiece” adaptation of the popular Hilary Mantel historical novels.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
There’s nothing worse than a boss who says one thing and does another, and nothing better than one who keeps his word. Just as managers must trust their team, employees must trust their boss to have their best interests at heart。
Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
'For now she wears a dab of lipstick and nail varnish.'
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
According to a report by Beijing Statistics Bureau, retail sales of consumer goods in the Chinese capital surpassed 1 trillion yuan ($152 billion) in 2015, up 7.3 percent year on year.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
There are many more 2016 movie releases that will do well at the box office, but there are only a few that we're all eagerly waiting to watch.
圣加伦大学校友的薪资排名第三，为114449美元（按购买力平价调整后），排在艾哈迈达巴德的印度管理学院(Indian Institute of Management)和印度管理学院班加罗尔分校(IIM Bangalore)之后，这两所商学院校友的平均薪资分别为116476美元和116094美元。圣加伦大学还在职业服务质量方面排名第一。
The Warriors are one of the best teams in NBA history, and you can put their championship run up against any team in NBA history for the best playoff performance ever. But there's also a legitimate question of what this means for the sport. If the best or second-best player of all time stands no chance against this team, what does it mean for the sport's competitiveness? It hasn't been a problem so far, thanks to an extremely wild offseason, but the question remains: what happens to a competitive sports league when it's not truly competitive at the highest level?
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
PRICE PER SQUARE FOOT: $395
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
A total of 3,077 new cases of HIV infection took place in colleges and universities across China in 2017, according to the National Health Commission (NHC) at a press conference on Friday.
Spielman was sifting through dirt at the Emek Tzurim national park on the slopes of the Mount of Olives in Jerusalem when she noticed the small rectangular object.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Yes — just. Democrats will regain control of the House of Representatives in the November midterm elections. Though they will not take charge until January 2019, they will waste no time preparing the House Judiciary paperwork. Mr Trump will label it a “witch hunt”. But another year of his surreal presidency makes it all but inevitable Democrats will campaign on a pledge to hold him to account. Whatever Robert Mueller’s investigation unearths before then is unlikely to turn enough Republicans against him.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
We will deepen rural reform.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
I was waiting for you to bring up the Nets’ situation, so fine, I'll do it here. Jeremy Lin's been out for weeks with a hamstring injury. They're the only team tanking correctly and they're not actually tanking!
Sweden’s foreign minister, Margot Wallstrom, a proponent of a “feminist foreign policy,” opened up to Ellen Barry about her abuse at the hands of an old boyfriend when she was a young woman, something she had never said publicly before.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Jennifer Lawrence is one of the hottest young actresses in Hollywood right now, so it's no surprise that a lot of men find her to be irresistible.
China’s investment in Europe and the US has reached record highs, despite the slowdown in the country’s domestic economy.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
WHAT: A riverfront contemporary with three bedrooms and three and a half bathrooms
Qatar University claimed the most international institution, marking the first time a Middle Eastern university has topped the list.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
EMBAGlobal is the only programme in the top 10 that saw a slight drop in the average salary of its alumni compared with last year (the other nine recorded strong increases).
If you have been out of work for a long time, it may be time to consider taking a job you wouldn't have looked at before.
A modular microarray imaging system for highly specific COVID-19 antibody testing
The fastest growing start-ups tend to be global in their outlook. The immigration restrictions already imposed by President Trump in the US and those under consideration as part of the UK’s separation from the EU are likely to be a hindrance in the coming year for hiring.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Among the top 10, four of them -- Pony Ma, Jack Ma, Ding Lei (CEO of Chinese game developer NetEase Inc) and Lei Jun (founder of smartphone maker Xiaoxi) -- are from TMT (telecommunications, media and technology) sectors.
And a few stopped to change a tire for an elderly French couple.
China’s investment in Europe and the US has reached record highs, despite the slowdown in the country’s domestic economy.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
A schoolgirl aged 11 has been honoured as "America's top young scientist" for inventing a quick, low-cost test to detect lead-contaminated water.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
1. The 2012 Ig nobel Psychology Prize
（美联社）波多黎各，圣胡安市 － 波多黎各新总督周一宣誓就职，作为美国领土许多人认为要为新的紧缩措施做准备，并为该岛摆脱严重的经济危机重新推动建州或独立。
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
The standout is "Him," a tear-jerker about queer love and cultural intolerance that, in its understated way, is an LGBTQ civil rights anthem.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The soaring prices of 2008, when oil reached more than $140 a barrel, will repeat, though not likely in 2014, Mr. Hummel said. The price 'is going to go higher.'
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
The film version of the popular television series "Legend of Sword and Fairy", also known as Chinese Paladin starts shooting in Zhejiang Province today.
Mr Williams notes that early November data from the likes of Brazil, Vietnam, Taiwan and Chile suggests the picture has continued to improve since October.
The ranking is in part based on how successful alumni have been in their careers, as reflected in the salary data.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
This is a story about six friends with precarious love lives who spend their days sitting in a cafe sipping coffee from oversized mugs. Who’d have thought this premise would go on to become one of the most influential sitcoms of all time?
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Entrepreneurs are movers and shakers. They can’t afford to analyze every detail or they’d never get anywhere. There is no place for procrastination in a startup. It’s a 24/7, no-vacation-or-sick-days kind of job that demands constant forward momentum. Make a brief assessment at every step and move on it. Trust your instincts.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
9. Am I spending too much? Overspending can lead to stress, clutter, and financial complications. It can also turn into a nasty habit over time. Saving money is an excellent practice and you will more than likely be glad you did in case of an emergency.
Anti-HIV drug repurposing against SARS-CoV-2
Length-scale dependence of protein hydration-shell density
PwC, the accountancy firm that has been responsible for counting Oscars votes for 80 years and ensuring that the correct envelopes are handed to presenters, swiftly apologised to the films, the presenters and the audience for giving the prize announcement for the wrong category to Beatty and Dunaway.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
After years working with large consumer product companies like Stride Rite and Keds, Pieri grew frustrated with the difficulty mom-and-pop shops had launching new products. "The more innovative a product—as opposed to mainstream and "known"—the harder it was to get distribution," she explains. In response, she launched The Grommet, a discovery platform that connects customers with inventors' stories and their products, five years ago. Pieri, whose company helped launch products including SodaStream and Fitbit, counts HP CEO Meg Whitman as a mentor and has a side-gig as an entrepreneur in residence at Harvard Business School.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
I may say "I'm terminating you because you didn't meet performance measures." I'm not going to say it's because you're a pain in the butt and piss people off every time you interact with them.
Box office sales in the world's second largest film market have posted average growth of 35 percent year on year since 2003. In 2015 alone, it grew a whopping 48.7 percent, according to the State Administration of Press, Publication, Radio, Film and Television (SARFT).
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